ERr 731® Supplements (Siberian rhubarb)

ERr 731® is an extract of Siberian rhubarb (Rheum rhaponticum) root that has been studied for its role in supporting women through perimenopause.

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Unlike hormone therapy, ERr 731® is a non-hormonal, plant-based option that has been researched for its potential to help relieve common menopausal symptoms such as hot flushes, night sweats, mood changes, and sleep disturbances.

What is ERr 731® and how is it different from ordinary rhubarb root extract?

ERr 731® is a standardised extract made specifically from Siberian rhubarb root. Unlike culinary rhubarb or other rhubarb species, this extract is carefully prepared to contain consistent levels of key compounds, mainly rhaponticin. Because it has been clinically evaluated in menopause research, ERr 731® is different from ordinary rhubarb root, it’s standardised, tested, and designed to provide reliable support as a non-hormonal option.

Supplements with ERr 731®

When choosing a supplement, look for clear labelling that names ERr 731® or Rheum rhaponticum extract, a standardised dosage and evidence-based formulations that have been studied in clinical trials. Choosing a trusted brand also helps ensure the product meets high standards.

What menopause symptoms can ERr 731® help relieve?

The strongest evidence is for vasomotor support, studies show ERr 731® may help reduce the frequency and intensity of hot flushes and night sweats. Research has also found improvements in emotional wellbeing, with perimenopausal women reporting less irritability, anxiety, and mood swings over time. Sleep quality is another area where benefits have been observed, with many perimenopausal women experiencing better rest and reduced tiredness.

What do scientific studies say about ERr 731’s® effectiveness?

ERr 731® has been the subject of multiple clinical trials and reviews, which consistently highlight its role in supporting women during perimenopause.

In one 12-week placebo-controlled study of perimenopausal women, those taking ERr 731® reported significant improvements across a wide range of symptoms, including the relief of hot flushes, compared to the control group.¹

Longer studies of up to six months also showed that overall menopause symptom scores dropped significantly with ERr 731®.²

More recently, a meta-analysis pooling several high-quality trials confirmed that women taking ERr 731® experienced greater improvements in symptom ratings than those who did not.³

1. Heger M, et al. Menopause 2006;13(5):744-59.

2. Kaszkin-Betta M, et al. Altern Ther Health Med. 2008;14(6):32-8.

3. Dubey VP, et al. J Biomed Res. 2024;38(3):278-286.

What dosage of ERr 731® is recommended?

Clinical trials have generally used a simple, once-daily dose of ERr 731®. Most studies found that one tablet per day, typically providing around 4 mg of the ERr 731® extract, was sufficient to deliver benefits. Always read the label and follow the directions for use.

What You Might be Wondering?

  • What is ERr 731® Siberian rhubarb?

    ERr 731® is a standardised extract derived from the root of rhapontic rhubarb, also known as Siberian rhubarb. It is a plant-based ingredient that has been used in research to explore its effects on certain aspects of women’s health during midlife transition or perimenopause.

  • What is rhapontic rhubarb root extract for menopause?

    Rhapontic rhubarb root extract is a concentrated form of the root of the rhubarb plant. It is often included in supplements aimed at relieving menopausal symptoms in perimenopausal women. 

  • What are the benefits of rhapontic rhubarb root extract?

    Clinical studies have investigated rhapontic rhubarb root extract for its potential to support wellbeing in midlife women. Reported outcomes in clinical studies include the relief of menopausal symptoms in perimenopausal women, such as hot flushes, moodiness and irritability.

  • How does ERr 731® compare to ordinary rhubarb root extract?

    ERr 731® is a standardised form of rhapontic rhubarb root extract. Standardisation ensures that each dose contains consistent levels of specific compounds, which may differ from ordinary rhubarb root extracts.

  • What is rhubarb root extract used for?

    Rhubarb root extract can be used as an ingredient in supplements formulated for the relief of menopausal symptoms during menopause.

  • How much rhubarb extract per day?

    Recommended daily amounts can vary depending on the specific product and formulation. Consumers should follow the dosing instructions provided on the supplement packaging or seek advice from a qualified health professional.

  • What does rhubarb do to the human body?

    Rhubarb contains plant compounds that are absorbed by the body when consumed as part of a supplement. The standardised extract ERr 731® is made from Siberian rhubarb root which is used to relieve menopausal symptoms during menopause.  

  • Does rhubarb extract help with menopause?

    Rhubarb extract, including ERr 731®, has been shown to support general health and wellbeing in women during menopause. Always read the label and follow the directions for use. Supplements should be taken as part of a broader approach to health and lifestyle.